The phosphate salt of codeine occurs as white, needle-formed crystals or white crystalline powder. Codeine phosphate is freely soluble in drinking water and slightly soluble in Liquor. The molecular fat is 406.37. Its molecular formula is C18H21NO3•H3PO4 • ½ H2O, and it's the following chemical composition.
When employed for an prolonged time, this medication may well not work in addition and could have to have different dosing. Chat with your physician if this medication stops working nicely.
Promethazine Promethazine competitively antagonize H1 receptors located in almost all of the smooth muscle such as the gastrointestinal tract, uterus, huge blood vessels and bronchial muscle.
Get health care aid without delay if you discover any of the subsequent: gradual/shallow breathing, severe drowsiness/difficulty waking up, confusion.
Browse the Medication Guidebook provided by your pharmacist Before you begin getting codeine/promethazine and each time you receive a refill. In case you have any inquiries, check with your physician or pharmacist.
Stimulation could be apparent, particularly in young children and geriatric sufferers. Convulsions may well almost never occur. A paradoxical reaction is documented in young children acquiring solitary doses of 75 mg to one hundred twenty five mg orally, characterized by hyperexcitability and nightmares.
Codeine and promethazine, two of your active substances in Promethazine with Codeine Oral Option, may well deliver marked drowsiness and impair the mental and/or Bodily capabilities needed for your efficiency of potentially dangerous responsibilities which include driving a car or truck or running machinery. Suggest people in order to avoid partaking in hazardous tasks necessitating mental alertness and motor coordination following ingestion of Promethazine with Codeine Oral Remedy.
Very carefully measure the dose utilizing a Unique measuring unit/spoon. Tend not to make use of a home spoon as you may not get the right dose.
An opioid antagonist, including naloxone, have to be accessible for reversal of opioid-induced respiratory melancholy while in the neonate. Opioids, like Promethazine with Codeine Oral Remedy, can lengthen labor through steps which briefly reduce the toughness, length, and frequency of uterine contractions. Nonetheless, this effect is not really reliable and will be offset by an increased amount of cervical dilation, which tends to shorten labor. Monitor neonates subjected to opioids in the course of labor for indications of surplus sedation and respiratory despair.
” Increased tension as part of your head (enhanced intracranial strain). Keep away from using PROMETHAZINE WITH CODEINE ORAL Answer When you have a head injury or have been explained to that you've got adjustments in the tissue of your respective brain (brain lesions) or amplified strain in your head. Neuroleptic malignant syndrome (NMS) which may result in Loss of life. Show you Health care supplier at once In case you have any of the subsequent indicators of NMS: substantial fever
Codeine is altered into a solid opioid drug (morphine) in One's body. In lots of people, this variation comes about quicker plus more entirely than regular, which raises the chance of pretty significant side effects.
Choose this medication precisely as prescribed to reduced the chance of habit. Question your health care provider or pharmacist For additional aspects.
Hardly ever share this medicine with another particular person, Specifically anyone with a historical past of drug abuse or habit. MISUSE Can result in Dependancy, OVERDOSE, OR Demise. Maintain the get more info medication in a location the place Some others cannot get to it. Selling or giving away this medication is versus the law.
When useful for an prolonged time, this medication may well not function at the same time and should involve various dosing. Discuss with your health practitioner if this medication stops working nicely.